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Can You Mix CBD With Other Pet Supplements?

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Can You Mix CBD With Other Pet Supplements?

Posted by Michael Jones on
Updated at: February 21, 2021

CBD and Medication

With CBD making such a huge splash on the medication market, many are still wondering how the supplement interacts with other supplements as well as medications your vet may prescribe.

While CBD is largely an incredibly safe product to use for a huge variety of conditions and illnesses, there are some medications it may not get along with. Having an understanding of these medications and what options you have can help you to make sure your pet is getting the best care.

Consequently, we're taking a close look into what CBD is, how it can help, and what medications you should be careful using it with. Armed with this knowledge, you'll know your pet is able to trust that they are in good hands, even when mixing medications.

What Is CBD For Dogs?

Many of these benefits stem from its natural anti-inflammatory nature. By treating inflammation in the body, those who use it can be left feeling happier and healthier in a number of ways. On top of that, it's useful for pets and humans alike.

Is CBD For Dogs Safe By Itself?

Some can confuse CBD for cannabis. While there is some truth to the initial origin of the substance, these days CBD is created through hemp plants that avoid unwanted substances. Instead, we are left with a healthy, safe, and helpful product that can help your pet in many ways.

By itself, CBD doesn't create unpleasant side effects such as those we see in many of the prescribed medications used today. At most, it can make your pet a bit sleepy if they are dosed with a high amount. However, in small amounts, they can actually get a bit of an energy boost. There are really few CBD negative side effects that have been discovered so far.

CBD And The Liver

By itself, CBD is thought to be safe for the liver. However, it's important to understand how it can affect other medications that require efficient processing in the liver in order to help. Medications like anti-epileptics and NSAIDs use the liver for the sake of digesting and using the medicine.

In order to do this well, the liver produces specialized enzymes by the name of cytochrome P450. In short, these enzymes make use of oxidization to make the medications easier to process.

Meanwhile, CBD, such as CBD oil and CBD oil pills, can cause those specialized enzymes to become inhibited. This makes the process of breaking down those medications more difficult, which results in the effects of those medications staying around longer. The medications aren't being broken down normally.

It's also worth keeping in mind that these effects on the liver can vary depending on the amount of CBD you give your pet.

CBD Medication Interactions

CBD is typically very safe, but it can cause problems when interacting with certain kinds of medications. This is especially true when the dose of CBD is on the higher end. In the following section, we'll dive into the CBD oil and drug interactions that can sometimes occur.

CBD Drug Interactions

Now that we've discussed the effects that CBD can have with the liver and other pet medications, it's time to take a look at some common medications this problem can occur with. Keep in mind that the following list is just a small snapshot. There are many medications out there that require the use of P450 enzymes.

Common medications that can be affected by CBD use are as follows:

  • Steroids, including options like Fludrocortisone and Prednisone
  • Benzodiazepines
  • Anesthetics
  • NSAIDs
  • Antihistamines
  • Fentanyl
  • Some kinds of antibiotics

Some common potential interactions you'll want to be aware of are Prednisone interactions, Tramadol interactions, Meloxicam interactions and those that may show up for Gabapentin for dogs.

Regardless of the medication, your pet may need, it's a good idea to talk to your vet about the interactions it may have with CBD, just to be on the safe side. It's always helpful to know what drugs should not be taken with CBD.

Using CBD Safely

Generally, CBD is thought to be very safe.

However, it's still important to know the ins and outs of the supplement as well as how it can react with medications for dogs and other pets. On that note, it's wise to think about the medications or supplements you already give your pet before you start adding CBD into the mix.

In addition, it can be a good idea to talk to your vet about the interactions that can occur. If the medication is for temporary use, you can just wait until the course is finished. Otherwise, you may want to look for ways to adjust the doses so that your pet can get the benefits of both without strong interactions.

You can also look for other medication options that allow you to use both without potential problems.

There may also be some other kinds of medications that you'll want to consider when looking into CBD. For example, understanding CBD oil and antidepressant interactions can be useful, though this does tend to be more applicable to humans. The same can also be true for CBD oil and blood pressure medications.

CBD Side Effects

CBD isn't known for having many side effects when used by itself or with medications or supplements that it doesn't interact poorly with. In high doses, it can sometimes make pets a bit drowsy but at this point, that is the extent of side effects that have been found.

Other Natural Supplements For Pets

As you're looking into CBD, it's likely you'll come across some other natural supplements for pets as well. These supplements can also be useful in keeping your pet feeling their best. You may find these popular supplement options especially helpful!

Fatty Acids

Fatty acids, specifically Omega-3, are fantastic for pets in a number of ways. They can help with keeping your pet's coat looking healthy and shiny. Because of that, they make for a great option when their coat is looking a bit dull, or if your pet is experiencing dry skin, dandruff, or other skin issues.

In addition, this is a great supplemental choice for handling inflammation in the body. While it may not be as powerful as medications that can be prescribed to your pet, it's a great way to provide them some comfort from things like arthritis, or mild forms of discomfort.


For pets who are suffering from arthritis, glucosamine can be a fantastic supplement to help them with getting around more comfortably. While it's not always extremely helpful in humans suffering from arthritis, it certainly can be helpful to our pets. As a result, it's worth looking into if your dog is showing signs of arthritis.

If you're interested in using this supplement for your pet, it's a good idea to compare it to other anti-inflammation options. You're sure to find an option that works well for helping your arthritic pet with moving around when they might otherwise struggle with the pain and stiffness.


Antioxidants are also an excellent way to help your pet with a number of functions. For example, dogs suffering from memory problems can benefit from vitamins E and C, which are capable of inflammation reduction. On top of that, there is a multitude of other vitamins that can provide your dog a boost.

Using Natural Supplements

There are a few things to consider when it comes to providing supplements to your pets. While they are typically safe, it's always a good idea to make sure you're providing the right dosages. Furthermore, it's going to be important to make sure you aren't mixing the supplements with other supplements or medications that may cause problems.

Because of this, it's always a good idea to talk to your vet about any supplement you're thinking about using. They can help you to get a good idea about how effective the supplement might be, whether or not it will affect other medications or supplements your pet may already be taking, and whether there might be better options.

The more you know about the supplements you plan to use, the better. It's also a good idea to avoid grabbing just any version of the supplements you can find. Instead, finding reputable brands with transparency in regard to ingredients is very important.

Furthermore, steer clear of supplements that promise more than they can offer. While supplements can be helpful with symptoms, they cannot cure serious illnesses and should not be used to replace their medications completely to avoid prescription interactions or supplement interactions.

The Benefits Of CBD

The side effects of CBD tend to be far outweighed by the benefits, which is why it has become such a popular supplement. Many of us are so sick of the side effects that come alongside popular medications.

A few CBD benefits include:

PurCBD | Innovet Pet
  • Stress and anxiety relief
  • Regulation of metabolic activity
  • Anti-inflammatory properties
  • Allergy relief
  • Nausea relief
  • Epilepsy relief

CBD is a highly valuable and versatile product, which makes it great for just about any pet. There are a few reasons not to give it a shot and see what it can do for your pet!

CBD For Pets

CBD is quickly becoming one of the most popular supplement options out there. This is due to the effectiveness and versatility of the substance. Healthy pets can even benefit from taking this as a preventative measure, helping to maintain their health longer.

There are also a wide variety of CBD products suited to different kinds of pets. For example, Innovet offers a variety of treats for dogs and horses, ensuring that each animal can easily get what they need. Otherwise, you can also use CBD oil for dogs, horses, or cats quite easily.

CBD is being investigated all over the world for many uses. However at this time, as the manufacturer of CBD products, we are not allowed to discuss that subject publicly nor we are not allowed to imply that CBD can be used for any specific treatment.

Top CBD Products

When it comes to CBD, quality products are key. They ensure that you can get the best results when it comes to helping your pet while keeping them safe from chemicals that the hemp plants can absorb. Due to that absorbent ability, it's highly important to get organic CBD pet products.

Second to that, you'll want to find the form of CBD that works best for your pet. Some will easily take CBD treats or even capsules, while others need something a bit more subtle. Luckily, Innovet offers just about everything your pet might need!


Most Trusted Pet Company | Innovet Pet

CBD oil is a popular option due to the versatile nature it offers. You can easily get CBD oil for cats, dogs, and horses and it tends to be extremely easy to administer. Most pets won't have a problem with a drop or two placed into their mouths, assuming you can get them to sit still for it!

For those that aren't, the oil can easily be mixed into their meals and they aren't likely to notice. Just make sure to get the concentration that is right for your pet, a little bit can also go a long way. Because of that, it's not something you're likely to have to purchase too often.

The CBD oil interactions that might occur are worth having an understanding of before you give the supplement to your pet.

CBD Treats

Many dog owners appreciate the ease of CBD dog treats. These treats come in some delightful flavors like maple bacon and berries, steak and cheese, and salmon with sweet potato. It'll be like a delicious dinner in your pet's mouth, making it so easy to give them the supplements they need!

In addition, Innovet ensures you can give your pet the correct amount by providing a handy guide on the back of each package. From small dogs to large, you'll know just what they need. For smaller dogs, they also offer soft treats that can break down a bit more easily into the right dose.

Just like with any CBD product, just make sure to talk to your vet about how these treats can interact with dog meds.

CBD For Dogs: The Bottom Line

While CBD is a safe product generally, make sure to talk to your vet before adding it to your pet's routine. This is going to be especially necessary if they are using other supplements or medications currently. Making sure that there won't be negative interactions is key to keeping your pet safe.

With the help of your vet, you can make sure that your pet is getting the best care. Assuming that your pet isn't on medications that it might interfere with, or that arrangements can be made for them to take both safely, there are few reasons not to give CBD a shot for the sake of your pet's health.


Approved by:

Dr. Ivana Vukasinovic

Doctor of Veterinary Medicine, University of Belgrade

Ivana Vukasinovic grew up in Serbia and attended the University of Belgrade where she received a degree in Veterinary medicine in 2012 and later completed surgical residency working mostly with livestock. Her first year of practice was split between busy small animal practice and emergency clinic, and after two more years of treating many different species of animals, she opened her own veterinary pharmacy where an interest in canine and feline nutrition emerged with an accent on fighting animal obesity. In her free time, she acts as a foster parent for stray animals before their adoption, likes to read SF books and making salted caramel cookies.












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The Innovet Team



    Please do not ask for emergency or specific medical questions about your pets in the comments. Innovet Pet Products is unable to provide you with specific medical advice or counseling. A detailed physical exam, patient history, and an established veterinarian are required to provide specific medical advice. If you are worried that your pet requires emergency attention or if you have specific medical questions related to your pet’s current or chronic health conditions, please contact or visit your local/preferred veterinarian, an animal-specific poison control hotline, or your local emergency veterinary care center.

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