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Denamarin For Dogs: Complete Information Guide

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Denamarin For Dogs: Complete Information Guide

Posted by AdKitan AdKitan on
Updated at: December 14, 2020

Denamarin for Dogs | Innovet Pet

Denamarin for dogs is a supplement given to dogs that need liver support. It is a supplement medication that can help increase antioxidants in the body that assist with liver function. Veterinarians will often prescribe it for certain conditions in which the liver is being affected negatively.


1. What Exactly Is Nutramax Denamarin For Dogs?
2. Denamarin For Dogs: How Does It Work?
3. What Causes Liver Disease In Dogs?
4. Most Common Causes of Canine Liver Disease 
5. Symptoms Of Liver Disease In Dogs
6. Denamarin For Dogs: Primary Uses
7. Which Is Better: Denamarin Or Milk Thistle For Dogs?
8. Can Denamarin Help With Liver Disease?
9. Dosage And Types Of Nutramax Denamarin For Dogs
10. Side Effects Of Denamarin For Dogs
11. Should I Give My Dog Denamarin?
12. What Else Can I Do For My Dog With Liver Disease?
13. CBD As A Natural Treatment For Dogs with Liver Conditions
14. Final Thoughts On Denamarin For Dogs

It is often used for liver failure, liver disease, and other liver conditions. It can reverse liver damage in some cases.

What Exactly Is Nutramax Denamarin For Dogs?

Healthy Dogs | Innovet Pet

Denamarin is a prescription supplement that is prescribed by a veterinarian for liver disease or damage and is often given to both felines and dogs. It can prevent or reverse liver damage, in some cases, and help elevate liver enzymes and healthy functioning.

Denamarin For Dogs: How Does It Work?

Denamarin for dogs works by utilizing s-adenosylmethionine and silybin to strengthen necessary liver function. They work together to increase liver enzymes and functions that are crucial to the healthy functioning of the liver organ. This supplement is relatively low-risk for dogs to take for their liver health and functioning needs. These two elements can increase liver function and even help with brain functioning.

What Causes Liver Disease In Dogs?

Unfortunately, liver disease can be dangerous for a dog's health. This is because the liver is a vital organ that is responsible for many important functions in the body of humans and animals. A dog's liver is what helps to purify the blood, allow for food digestion, and eliminates the waste that is in the body. This is why the liver being unhealthy can be quite damaging to the health and livelihood of your pet.

Most Common Causes Of Canine Liver Disease

The most common causes of canine liver disease are:

Denamarin For Dogs | Innovet Pet
  • Metabolic disease
  • Bacterial infections
  • Improper diet
  • Infections that are viral
  • Trauma or injury
  • Toxicity (chemicals)
  • Drugs (like acetaminophen, other drugs with liver damage as a side effect)
  • Poison ingestion
  • Genetics
  • Abnormalities (congenital malformation)
  • Over-vaccination

An improper diet is one of the biggest causes of liver damage or liver disease. In most cases, improper diet due to nutritional imbalance caused by parasites or intestinal issues some of the more typical causes of liver damage. In some cases, some dogs are fed a diet that is filled with starches and proteins that can affect the liver negatively. This is not good for dogs that have an especially sensitive liver function. It can cause liver damage that some veterinarians encounter. Also, giving them too much food at once isn't good for them. Dogs should be fed according to the guidelines given by vets and as recommended by serving sizes and weights. Liver disease or damage from a poor diet can be easily corrected. It is crucial to follow the veterinarian's recommended guidelines and food choices if your dog has been diagnosed with this condition. Sometimes, they recommend making homemade foods that have specific ingredients. There are holistic veterinarians that can help with diet recommendations. 

Some medicines, like acetaminophen, can cause liver damage. This is true for dogs just as it is for humans. Pet parents that have canine taking acetaminophen need to pay close attention to how their pet reacts and let their veterinarian know if they have been giving this medication. Make sure to only give your dog the recommended dosage of acetaminophen.

There are dog breeds that are more susceptible to liver disease. Terrier breeds like West Highland, Skye, Yorkshire, and Bedlington are at higher risk of developing liver disease. Also, Spaniel breeds and Dobermans are breeds that also have a genetic predisposition to these conditions. These breeds are at a higher risk for liver disease because their bodies are not able to eliminate copper as well as it should and this causes copper toxicity within the body. This copper toxicity affects the liver as this is the organ that is supposed to be able to eliminate it and it makes the levels get high within the liver as well.

The ingestion of poisons is often something that occurs by accident. Our furry friends love to eat things that they think looks or smells like food. Unfortunately, the accidental ingestion of a poison or toxic chemical can cause liver damage. It can range from minor to severe. If a dog accidentally ingests poison they need to be rushed to the veterinarian emergency room as soon as possible. It could save their lives to get to the vet right away and may be able to limit the damage to their liver and other organs. Pet parents that have chemicals or poisons around the home should put them on high shelves or places that are locked.

Congenital malformation sometimes occurs that affect the liver. Sometimes, dogs are born with abnormal liver formation or another defect that makes it harder for the liver to get their job done. This is not something that can be prevented and is something that will require special care from a veterinarian for the duration of their lives. They may be on medications and supplements for the long-term.

Over-vaccination is something that can occur. Sometimes, a pet parent hasn't kept track of the vaccination records or has lost them and they don't know when the last time their furry friend was vaccinated. Also, sometimes a person adopts a pet and they don't know their vaccination record at all. This leads to a pet getting vaccinated before it is time. Over-vaccination can cause liver disease and pet parents should do whatever they can to keep accurate track of their dog's vaccinations. Most veterinary offices have a record of the pet's vaccination history on file.

Bacterial and viral infections are usually things that cannot be helped. They come out of nowhere and make precious pets sick. Fortunately, most infections go away with the proper treatment without any long-term side effects. However, that is not always the case and sometimes dogs suffer liver damage, particularly leptospirosis, infectious canine hepatitis, and canine adenovirus 1.

Symptoms Of Liver Disease In Dogs

Symptoms of Denamarin for Dogs | Innovet Pet

The symptoms of liver disease in dogs are greatly varying in severity and types. Most pet parents are unable to tell that their dog is suffering from this until they become very ill. Some of the symptoms resemble many other ailments.

The most common early symptoms of liver disease in dogs is diarrhea, vomiting, lethargy, dark urine, and lack of appetite. A late-stage symptom of liver disease that is a sign that it is progressing is that the eyes will begin forming jaundice (yellow eyes). If you notice that your precious pet has yellowed eyes, it is necessary to get them to the veterinarian right away.

Dogs that are suffering from obesity or diabetes often have a higher incidence of liver damage and disease. Obese or overweight dogs can lose weight and perhaps stop liver damage or even reverse it. It is a good idea to discuss a diet with the veterinarian and begin exercising them more often. Many vets will recommend a more organic and less processed diet that has fewer carbohydrates and grains than many commercial dog foods. Diabetic dogs will almost always have to start a healthier diet right away and there is a link between diabetes and liver disease. Diabetic dogs that don't get their weight and blood sugar under control can begin suffering from numerous health problems. They can have liver damage, kidney damage, and much more. Veterinarians will want to see dogs with diabetes on a regular basis in order to monitor their health and progression.

Trauma to the body or the liver can also cause liver disease in dogs. For example, a dog that is hit by a car may suffer trauma to the body. These injuries can leave long-lasting injuries and side effects. Dogs that have suffered bodily trauma may need to have more than the average number of veterinary visits to ensure that they are doing well. This is also to enable the veterinarian to catch any issues as soon as possible and treat them immediately. Pet parents will have to keep a close eye on their beloved pet after an injury to the body.

Denamarin For Dogs: Primary Uses

Denamarin for dogs is used for liver disease and liver damage. Dogs that have genetic conditions, liver abnormalities, and other issues sometimes have liver disease that is chronic. These dogs can benefit from Denamarin to help with elevating liver enzymes and essential functions so that they are able to manage their condition. Liver damage can sometimes be stopped and reversed with Denamarin. Dogs that have liver damage from trauma or illness can sometimes see a reversal of the condition. In many cases, the damage can be stopped in its tracks and no further damage will occur.

Which Is Better: Denamarin Or Milk Thistle For Dogs?

The compound silymarin is present in Denamarin and milk thistle. Denamarin has an additional compound, s-adenosylmethionine, that assists with brain function and liver function. Because of this, Denamarin for dogs is a better choice than milk thistle. Milk thistle does not have s-adenosylmethionine and therefore does not offer as many health benefits as Denamarin.

Can Denamarin Help With Liver Disease?

Denamarin is not a cure for liver disease. It can help with reversing liver damage and with elevating liver enzymes and really help a dog that is dealing with this condition. There is no known cure for liver disease.

Dosage and Types Of Nutramax Denamarin For Dogs

Denamarin is a prescription medication that can be prescribed by a veterinarian. It is available in a chewable and coated form. The dosage of Denamarin will vary based on the weight and age of your dog. The veterinarian will let you know the recommended dosage based on your pet's body weight and age. The prescribing service should also give pet parents instructions on dosage and frequency. It is imperative to follow these instructions so that your dog doesn't accidentally get too much Denamarin. There are consequences to accidentally giving your dog too much Denamarin.

Side Effects Of Denamarin For Dogs

There are not any significant side effects for dogs that take Denamarin. However, dogs that are given too much Denamarin may have vomiting and diarrhea. Vomiting and diarrhea from too much Denamarin can be very uncomfortable for your furry friend. This is why it is so crucial to stick to the prescription instructions and follow them to the letter. If you are worried that your pet has taken too much, it is a good idea to check in with the veterinarian. However, there have been no reported major side effects from taking too much Denamarin and it is likely that your dog will be fine as long as the overdosing is stopped. They may require electrolytes and rest for a while so that they can recover well.

Should I Give My Dog Denamarin?

Denamarin is a well-known and recognized prescription for dogs that have liver disease. It has been shown in studies to be effective with elevating liver enzymes, helping liver function, and even reversing damage to the liver. These studies confirm that it is an effective medication. It has no major side effects. Therefore, it is likely perfectly fine and safe to give your dog Denamarin and something that can benefit their liver health. Pet parents that are worried about the horrendous side effects of some prescriptions do not have to worry about it with this medication as they do with others. However, the ultimate decision on whether you should give your dog Denamarin should be between you and your trusted vet. It is important to discuss whether it will be beneficial to your dog's health. If your dog's veterinarian recommends it, then it is probably a wise idea to give it to your canine as prescribed. After all, every pet parent wants to see their dog get better after suffering from a medical condition that can be painful and difficult.

What Else Can I Do For My Dog With Liver Disease?

Dogs that have the liver disease can live a healthy life for many years. They can live that long and healthy life with the help of pet parents that give them the proper medications and the best foods for their health condition. Ensuring that they have the right foods and medicines can make all of the difference in helping your dog with liver disease. Also, giving them plenty of attention and love always helps a lot! There are proven studies that show that dogs that are given attention and loving care are happier and healthier pets. That is something that a pet parent can do easily out of pure love and there is no cost to adding a little extra affection and care.

CBD As A Natural Aid For Dogs with Liver Conditions

Dogs that have liver conditions often deal with discomfort or pain of some sort. Unfortunately, pet parents can't always tell when their dog is in pain or suffering. Many pet parents love to give their pets something organic and natural to help them with their health. This is because natural options are without chemicals that can have devastating consequences. CBD is an example of a natural aid that is chemical-free and completely organic. It is derived from hemp extract and gives users amazing health benefits. There are numerous studies that show CBD can help with pain, inflammation, nausea, and much more. There are medical studies that have confirmed this. 

CBD Oil for Dogs | Innovet Pet

CBD is being investigated all over the world for many uses. However at this time, as the manufacturer of CBD products, we are not allowed to discuss that subject publicly nor we are not allowed to imply that CBD can be used for any specific treatment.

CBD Oil for dogs is specially formulated for pets in mind. It allows for easy dosing and can be given to dogs in their food or with their favorite treat. There are zero THC and zero side effects and that means that pet parents don't have to worry about any type of “high” and they also do not have to worry about side effects. There is really no downside to giving dogs CBD. Everything is very positive in that there are proven health benefits and no side effects. Many pet parents have seen improvements in the overall health of their dogs after a short period of time once they have begun taking CBD.  Dogs that have liver disease or have liver damage can experience an improvement in their well-being after taking this product and pet parents can give it to them without worry.

Final Thoughts On Denamarin For Dogs

Denamarin for dogs is a viable and helpful prescription that has shown effectiveness in treating liver disease and liver damage. It has been given as a prescription by vets for many years and has been tested in numerous studies as a safe and effective medication. Many dogs have had good results after taking Denamarin and it has benefited many pets. There are no severe side effects to worry about and that is quite amazing in that many prescriptions do have a long list of dangerous side effects.

In summation, Denamarin is safe to give dogs and can have a positive impact on their health. The side effects are not serious. Pet parents that are given this prescription for their dogs can move forward with confidence that it should help their health and improve their liver function.


Approved by:

Dr. Ivana Vukasinovic

Doctor of Veterinary Medicine, University of Belgrade

Ivana Vukasinovic grew up in Serbia and attended the University of Belgrade where she received a degree in Veterinary medicine in 2012 and later completed surgical residency working mostly with livestock. Her first year of practice was split between busy small animal practice and emergency clinic, and after two more years of treating many different species of animals, she opened her own veterinary pharmacy where an interest in canine and feline nutrition emerged with an accent on fighting animal obesity. In her free time, she acts as a foster parent for stray animals before their adoption, likes to read SF books and making salted caramel cookies.


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The Innovet Team

Please do not ask for emergency or specific medical questions about your pets in the comments. Innovet Pet Products is unable to provide you with specific medical advice or counseling. A detailed physical exam, patient history, and an established veterinarian are required to provide specific medical advice. If you are worried that your pet requires emergency attention or if you have specific medical questions related to your pet’s current or chronic health conditions, please contact or visit your local/preferred veterinarian, an animal-specific poison control hotline, or your local emergency veterinary care center.

Please share your experiences and stories, your opinions and feedback about this blog, or what you've learned that you'd like to share with others.


Innovet Pet Team - February 29, 2020

Hello Charles,

I’m sorry but I think it’s best to consult a veterinarian regarding that question just to be safe.

Charles K Whitten - February 29, 2020

Can I safely give Denamarin Advanced indefinitely on a daily basis for a pet with high liver enzymes detected in a blood test?

Innovet Pet Team - February 22, 2020

Hey Amy,

Due to liability issues, we can not provide advice when it comes to medications or prescriptions. Our customers use our product for many different things along with other medications. So many that, it is hard for us to keep track of. We created a Facebook group for our customers to discuss what they use our product for, what works and what doesn’t, etc. It is called Innovet Pet Talk & Support: CBD for Dogs, Cats, & More. Perhaps you can find more information there 🙂

Amy Herndon - February 22, 2020

Can denamarin and CBD oil be given simultaneously for liver support? I know CBD has few interactions but wanted to make sure the two wouldn’t be working against each other.

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