Best CBD Oil for Puppies: 5 Safe Options for Anxiety and Teething (2026)

• Which Is the Best CBD Oil for Puppies? 5 Options Ranked
  
• Is CBD Oil Safe for Puppies?
  
• How Does CBD Help Puppies?
  
• Which CBD Brand Offers the Best Deal for Puppies?
  
• Final Verdict: Which CBD Oil Is Best for Your Puppy?
  
• Frequently Asked Questions
  

Everyone talks about “puppy love,” but they forget to mention the sleepless nights. Crate training, separation anxiety, and teething pain can turn your cute new friend into a crying, chewing stress ball.

You want to help them relax, but most products on the shelf are made for big, adult dogs. Giving strong supplements to a tiny puppy with a sensitive tummy feels risky.

We wanted to find the best CBD oil for puppies that takes the worry out of it. We picked these five brands because they’re gentle, purity-tested, and have low enough doses to be safe for growing bodies.

Check out our best CBD oil for dogs if you have an adult dog instead.

Which Is the Best CBD Oil for Puppies? 5 Options Ranked

To keep your puppy safe, we looked for brands that offer low-potency options, pure ingredients, and no artificial additives that could upset a developing stomach.

Here’s the at-a-glance breakdown of the best CBD starter bottles for young dogs if you’re short on time:

Rank	Brand	Best For	Potency	Price	Subscription
#1	Innovet Pet	Growth and Safety	125 mg	$27.95	Save 20%
#2	Honest Paws	Crate Training	125 mg	$24.95	Save 15%
#3	HolistaPet	THC-Free	150 mg	$29.95	Save 20%
#4	Pet Releaf	Toy Breeds	100 mg	$26.99	Save 15%
#5	Charlotte’s Web	Trusted Legacy	510 mg (17 mg/mL)	$59.99	Save 30%*

*Note: Charlotte’s Web offers 35% off on the first order and 30% off on recurring orders if you subscribe.

1. Innovet Pet PurCBD+ - Best Overall for Growth and Safety

Innovet Pet’s CBD oil for puppies is the safest choice for young dogs due to its simple, two-ingredient purity and nutrient-rich carrier oil.

When you have a 5-pound puppy, you can’t take risks with fillers or chemicals. Innovet’s CBD oil for puppies is the standout winner for puppies because it keeps the formula cleaner than anyone else. The 125 mg bottle contains exactly two things: USDA Organic hemp extract and virgin hemp seed oil.

Unlike most competitors that use MCT (coconut) oil, this formula uses hemp seed oil. This carrier is packed with omegas 3, 6, and 9, which act as a superfood boost for a puppy’s growing brain and soft coat.

Most importantly, the 125 mg potency allows for ultra-precise micro-dosing. A single drop contains a tiny amount of CBD, meaning you can safely find the perfect dose for even the smallest teacup breeds without over-sedating them.

If your puppy is chewing everything in sight due to teething pain, you can rub a drop of this oil directly onto their gums for targeted relief.

Features

• Specifically formulated 125 mg concentration for precise micro-dosing.
• Rich in natural omegas to support brain and coat development.
• USDA Organic hemp extract without preservatives.
• Cold CO₂ extraction removes all harsh chemical solvents.
• Third-party lab tested for safety and purity.

Pros

• ✅ Hemp seed oil provides extra nutrients for growth.
• ✅ Simple formula is gentle on sensitive puppy stomachs.
• ✅ Very affordable entry price.
• ✅ Precise dosing allows for safe micro-adjustments.
• ✅ 30-day money-back guarantee.

Cons

• ❌ Natural “grassy” taste can be tricky for picky eaters.
• ❌ Glass dropper requires care around wiggly puppies.

Pricing

The 125 mg bottle is perfect for small breeds (Yorkies or Chihuahuas). For medium/large puppies (Labradors and Shepherds) that grow fast, the 250 mg bottle offers better long-term value while still being gentle enough to dose safely.

Bottle Strength	Retail Price	Price Per mg
125 mg (Small Puppy)	$27.95	$0.22/mg
250 mg (Medium/Large Puppy)	$39.95	$0.16/mg

Buying Tip: You can save 20% by subscribing.

2. Honest Paws Calm Oil - Best for Crate Training

Honest Paws’ chamomile-infused formula is designed specifically to help soothe puppies during crate training or night terrors.

If your main issue is “crate crying” (the howling, barking, and panic that happens when you leave the room), Honest Paws’ CBD oil for dogs is a good option. Their Calm formula stands out because it combines organic full-spectrum hemp with chamomile extract.

Chamomile is a natural relaxant known for soothing nervousness. By adding it to the oil, they create a blend targeted specifically at behavioral stress rather than just general health.

It uses organic MCT oil as the carrier. While this doesn’t have the same brain-boosting omegas as hemp seed oil, MCT digests quickly, which can offer faster relief when your puppy wakes up crying at 2 a.m.

Features

• Infused with organic chamomile extract for extra relaxation.
• Carries the official USDA Organic seal.
• Uses organic MCT oil for fast digestion.
• Condition-specific formula for sleep and anxiety support.
• Third-party lab tested for purity.

Pros

• ✅ Chamomile helps with sleep better than CBD alone.
• ✅ Great for high-stress moments like vet visits.
• ✅ USDA certification offers peace of mind for new owners.
• ✅ Dropper is easy to use for small mouths.

Cons

• ❌ Chamomile adds a floral flavor some puppies might reject.
• ❌ MCT oil lacks the skin and coat benefits of hemp seed oil.
• ❌ Cost per milligram is slightly higher on larger bottle sizes.

Pricing

The 125 mg bottle is priced competitively for new owners looking to try CBD for the first time without a huge investment.

Bottle Strength	Retail Price	Price Per mg
125 mg (Small Puppy)	$24.95	$0.20/mg

You might see Honest Paws offering “Mobility” (with turmeric) and “Well” (general health) options. While these are excellent products, they aren’t necessary for most puppies.

• Skip “Mobility” unless your puppy has diagnosed hip dysplasia. Puppies have brand new and healthy joints. They don’t need the extra turmeric or cost associated with joint and mobility support yet.
• Skip “Well” because the formula lacks the chamomile found in the “Calm” line. Since most puppy parents are struggling with sleep and training stress, you get better results sticking to the specific anxiety-support formula.

Buying Tip: If you subscribe, you can save 15%, bringing the price down to around $21 per bottle.

3. HolistaPet CBD Oil - Best THC-Free Option

The best choice for owners who want the peace of mind of a broad-spectrum CBD oil with absolutely zero THC is HolistaPet’s CBD oil.

While the trace amounts of THC in full-spectrum oil (less than 0.3%) are considered safe for dogs, some new puppy parents simply prefer to avoid it entirely. HolistaPet is our top recommendation for broad-spectrum CBD oil for puppies. They process their extract to remove every trace of THC while keeping other beneficial cannabinoids intact.

Like Innovet, they use hemp seed oil as the carrier instead of the coconut oil found in other brands. This makes it a nutritious choice, providing essential fatty acids that support healthy skin and a shiny puppy coat.

The 150 mg bottle is slightly more concentrated than Innovet’s starter size, meaning you can use a little less liquid per dose.

Features

• Broad-spectrum formula containing 0% THC while retaining other cannabinoids.
• Uses pure hemp seed oil as a carrier instead of MCT oil.
• Non-GMO, gluten-free, and dairy-free.
• Made in the USA from natural superfoods.
• Third-party tested for potency and solvent-free purity.

Pros

• ✅ Contains 0% THC, making it ideal for ultra-cautious owners worried about sensitivity.
• ✅ The hemp seed carrier boosts omega intake.
• ✅ The simple ingredients minimize the risk of upset tummies.
• ✅ The bundle deals make it easy to save if you buy 2 or 3 bottles at once.

Cons

• ❌ Without the trace THC, the oil might be slightly less potent for pain or teething than a full-spectrum alternative.
• ❌ Slightly more expensive than the other starter bottles on this list.

Pricing

The 150 mg bottle is their standard entry point for small pets. While a bit pricier per bottle, they offer good bulk discounts. Avoid the salmon and chicken flavors to minimize the risk of tummy upset, unless you have a picky puppy.

Bottle Strength	1-Pack Price	2-Pack Price	3-Pack Price	Price per mg (1-Pack)
150 mg (Small Puppy)	$29.95	$55.41	$76.37	$0.20/mg
300 mg (Medium/Large Puppy)	$39.95	$73.91	$101.87	$0.13/mg

Buying Tip: If you have multiple dogs or a rapidly growing puppy, buying the “3-pack” reduces the price per bottle significantly. You can also subscribe for repeat deliveries to save 20%.

4. Pet Releaf Daily Releaf (100 mg) - Best for Toy Breeds

Pet Releaf offers the lowest potency option on the market, making it the safest mathematical choice for teacup breeds like Yorkies or Chihuahuas.

If your new puppy weighs only 2 or 3 pounds, even a standard 125 mg bottle requires very careful dosing. Pet Releaf offers a 100 mg bottle, which gives you a slightly larger margin of error when measuring doses for micro-dogs.

It holds the USDA Organic seal, which is a major trust factor for parents worried about pesticides. We recommend this standard “Daily Releaf” oil over their more expensive “Liposomal” line. The liposomal version is too potent and expensive ($55+) for a puppy that just needs simple, gentle support.

Features

• USDA Organic full-spectrum hemp.
• 100 mg total potency per bottle.
• Organic MCT oil carrier.
• US Hemp Authority-certified.
• Extracted using supercritical CO₂.

Pros

• ✅ Lowest standard potency reduces risk for toy breeds.
• ✅ Organic certification provides safety assurance.
• ✅ Widely available in local pet stores for quick purchase.
• ✅ Safe for dogs with very low body weight.

Cons

• ❌ High cost per milligram ($0.27) compared to competitors.
• ❌ Glass dropper design often traps air bubbles.
• ❌ Not scalable for large breed puppies who grow quickly.

Pricing

The 100 mg bottle has a low entry price, making it a good “tester” bottle for tiny breeds, though it becomes expensive if your dog grows large.

Bottle Strength	Retail Price	Price Per mg
100 mg (Toy Breeds)	$26.99	$0.27/mg

Buying Tip: Pet Releaf is sold in thousands of independent pet retailers. If you need a bottle today because your puppy won’t stop crying, chances are you can find it locally. Otherwise, you can subscribe to save 15% off online orders.

5. Charlotte’s Web Hemp Extract for Dogs - Best Trusted Legacy Brand

Charlotte’s Web’s hemp extract for dogs is a premium option for owners who prioritize brand reputation and want a product backed by the NASC Quality Seal.

Charlotte’s Web is perhaps the most famous name in the industry. While they’re best known for human products, their canine line meets rigorous safety standards. The biggest trust signal here is the NASC Quality Seal; it’s a strict third-party audit that ensures the highest manufacturing standards.

For puppies, we recommend their 17 mg/mL oil (their standard concentration). It comes in two options: unflavored or a chicken flavor that helps with compliance for picky eaters. The unflavored option is the safest choice if you’re concerned about digestive upset.

However, you must be careful with the math. This oil is significantly more concentrated than the Innovet or Pet Releaf starter bottles. A single milliliter contains 17 mg of CBD. For a 10-lb puppy requiring only 1 to 2 mg, you’ll need to measure a tiny fraction of the dropper (0.1 mL) to avoid over-sedation.

Features

• Contains full-spectrum hemp extract sourced from US-grown hemp.
• Carries the NASC Quality Seal and U.S. Hemp Authority certification.
• Available in chicken or unflavored options.
• Uses MCT oil as the carrier.
• Concentrated formula (17 mg of CBD per 1 mL).

Pros

• ✅ NASC certification provides the highest level of industry trust.
• ✅ Chicken flavor encourages picky puppies to take it.
• ✅ Trusted global brand with a long history of safety.
• ✅ High-quality full-spectrum profile for calming support.

Cons

• ❌ High entry price ($59.99) compared to other starter options.
• ❌ High concentration makes “micro-dosing” difficult for toy breeds (under 5 lbs).
• ❌ The dropper is large, making tiny measurements tricky.

Pricing

This is a premium product with a higher upfront cost, though the higher concentration means the bottle lasts longer. However, because this is 4x stronger than Innovet’s puppy formula, use the dropper very carefully. Do not give a full dropper to a puppy.

Bottle Size	Total Potency	Price	Price Per mg
30 mL	510 mg	$59.99	$0.12/mg
100 mL	1,700 mg	$149.99	$0.09/mg

Buying Tip: You can save 35% on your first order and 30% on subsequent orders by subscribing.

Is CBD Oil Safe for Puppies?

The short answer is yes, but age matters. Most veterinarians and experts recommend waiting until your puppy is at least 8 to 12 weeks old before introducing any supplements.

At this young age, their digestive system and liver are still developing. While CBD has a high safety profile, you want to use the cleanest, gentlest product possible.

Our most important safety rule is to never give your puppy CBD oil meant for humans.

• Xylitol: Many human oils use artificial sweeteners like xylitol (birch sugar) to improve the taste. This is harmless to us but deadly toxic to dogs. It causes rapid liver failure.
• THC content: Human “full-spectrum” products can legally contain higher levels of THC or vary in consistency. A trace amount of THC that a human wouldn’t feel can send a 5-pound puppy to the emergency vet with wobbles and disorientation (static ataxia). Always stick to veterinary-formulated products.

How Does CBD Help Puppies?

While older dogs use CBD for arthritis, puppies have their own set of struggles. Here are the three main reasons new owners reach for the dropper:

1. Crate Training and Separation

The “first night home” is famous for howling and crying. Being separated from their litter is scary.

→ CBD interacts with receptors in the brain to support a sense of calm. It doesn’t sedate them; it simply helps lower the panic threshold so they can self-soothe and fall asleep in their crate.

2. Teething Relief

Between 12 and 24 weeks, puppies lose their baby teeth. Their gums become inflamed, painful, and itchy, leading to them chewing your shoes and baseboards.

→ CBD is a natural anti-inflammatory. Instead of putting the oil in their food, rub a drop directly onto their red, inflamed gums with your finger. This provides targeted topical relief.

3. Hyperactivity and Focus

All puppies get the “zoomies,” but some struggle to settle down enough to learn.

→ CBD can help take the edge off frantic energy by promoting a balanced mood. It makes it easier for your puppy to focus on training commands without falling asleep.

Which CBD Brand Offers the Best Deal for Puppies?

When buying for an adult dog, you might look for the strongest stuff at the cheapest price. But for puppies, the rules are different. Purity and dosing precision are far more important than raw power.

We compared the starter bottles from the top brands to see which one offers the safest, most nutritious formula for a growing body.

Brand	Bottle Size	Price	Price Per Drop (Approx.)	Carrier Oil
Innovet Pet	125 mg	$27.95	$0.06	Hemp Seed (Omega-Rich)
HolistaPet	150 mg	$29.95	$0.06	Hemp Seed (Omega-Rich)
Honest Paws	125 mg	$24.95	$0.05	MCT (Coconut)
Pet Releaf	100 mg	$26.99	$0.07	MCT (Coconut)
Charlotte’s Web	510 mg*	$59.99	$0.12	MCT (Coconut)

*Note: Charlotte’s Web doesn’t sell a low-dose starter bottle. Their smallest size is 510 mg (30 mL bottle) because they use a standard 17 mg/mL concentration.

1. Why Carrier Oils Matter for Puppies

Most brands (Honest Paws, Pet Releaf, and Charlotte’s Web) use MCT oil (coconut extract). While safe, it acts as a filler.

Innovet uses virgin hemp seed oil. This is important for puppies because hemp seeds are a natural superfood packed with omega 3, 6, and 9 fatty acids. A growing puppy needs these fats for healthy brain development and to fuel that super-soft puppy coat.

With Innovet, the carrier oil works just as hard as the CBD.

2. The Danger of Concentrated Options

Charlotte’s Web is a great brand, but their smallest bottle is 510 mg (17 mg per mL). This is very concentrated.

To give a 10-lb puppy a safe dose (1 mg), you’d need to measure just a tiny fraction of a milliliter. Trying to measure 1/10 of a dropper while a puppy is wiggling is difficult and risks an accidental overdose.

Innovet, Honest Paws, and Pet Releaf offer much milder concentrations (approx. 4 mg per mL), meaning you can give a few full drops safely without worry.

3. Cleanest Ingredient List

Puppies often have sensitive stomachs that react poorly to change. Innovet wins on simplicity: we use only two ingredients. There are no flavorings (like chicken or salmon additives) that could trigger allergies and no stevia or sugars.

It’s the closest thing to nature you can put in their bowl.

Final Verdict: Which CBD Oil Is Best for Your Puppy?

The “best” oil depends on your puppy’s specific challenges and size.

• If you have a tiny “toy” breed (under 3 lbs) and need the absolute lowest potency for safety, Pet Releaf is a great choice with their 100 mg bottle.
• If you want to avoid THC entirely because you’re worried about sensitivity, HolistaPet is the clear winner for broad-spectrum options.
• If you’re struggling with crate training and night terrors, Honest Paws offers a chamomile-infused blend that targets sleep specifically.

However, for most new owners who simply want to support their puppy's health, training, and growth, Innovet Pet is the logical winner.

Because puppies have developing systems, purity is everything. Our CBD oil for puppies formula uses just two ingredients (USDA Organic hemp and virgin hemp seed oil).

Choosing hemp seed oil over the cheaper coconut oil used by competitors helps you give your puppy a boost of essential omegas 3, 6, and 9 to support a healthy brain and a shiny new coat.

It’s the cleanest, most nutritious choice for a growing dog, all at a price that makes sense.

Frequently Asked Questions

How old does a puppy have to be to take CBD?

Ideally, at least 8 to 12 weeks. While CBD is safe, newborn puppies have very sensitive systems. Most vets recommend waiting until they’re weaned and have started their vaccinations before introducing supplements.

Why didn’t you list ElleVet Sciences for puppies?

They’re simply too strong for most puppies. ElleVet makes a fantastic product for senior dogs with severe pain, but their oil is highly concentrated (70 mg/mL). A 10lb puppy might only need 1mg of CBD.

Trying to measure that tiny amount with such a potent oil is difficult and risks accidental over-sedation. For puppies, we prefer brands with lower concentrations that allow for safer, easier micro-dosing.

Will CBD affect my puppy’s growth?

No, there’s no evidence that CBD stunts growth. In fact, using a product with a hemp seed carrier oil (like Innovet's) provides essential omegas 3, 6, and 9, which actually support healthy brain and bone development.

Can I give my puppy CBD with vaccines or dewormers?

We recommend pausing CBD for 24 hours. While there are no dangerous interactions, it’s best to let your puppy's immune system focus entirely on the vaccine or dewormer without having to process supplements at the same time.

What if my puppy drinks the whole CBD oil bottle?

Don't panic, but do call your vet. Because hemp CBD is non-toxic, this is rarely fatal, but it'll likely cause diarrhea and extreme drowsiness. However, if the product contained high THC or xylitol (common in human products), it’s an emergency. Keep them warm and hydrated while they sleep it off.

Will CBD stop my puppy from biting?

Indirectly, yes. CBD isn't a behavior trainer, so it won’t teach them "no bite." But if the biting is caused by teething pain or overstimulation (the "zoomies"), CBD helps soothe the inflammation and calm their mood, reducing the urge to nip.

How do I get my puppy to take CBD?

Use the "finger trick." If they don't like the dropper, put a drop of oil on your finger and rub it on their gums. If that fails, mix it with a tiny smear of peanut butter (xylitol-free!) or plain yogurt.